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Astellas Pharma and Dyno Therapeutics Sign Option and License Agreement

Will collaborate to develop next-gen AAV gene therapy vectors for skeletal and cardiac muscle.

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By: Charlie Sternberg

Associate Editor

Astellas Pharma Inc. and Dyno Therapeutics Inc. have signed an option and license agreement to develop next-generation adeno-associated virus (AAV) vectors for gene therapy directed to skeletal and cardiac muscle using Dyno’s CapsidMap platform.   Dyno’s CapsidMap platform represents a transformative approach applying in vivo experimental data and machine learning to create novel AAV capsids – the cell-targeting protein shells of viral vectors – designed to optimize tissue targeting ...

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